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Impact of Adenovirus E4-ORF3 Oligomerization and Protein Localization on Cellular Gene Expression

The Adenovirus E4-ORF3 protein facilitates virus replication through the relocalization of cellular proteins into nuclear inclusions termed tracks. This sequestration event disrupts antiviral properties associated with target proteins. Relocalization of Mre11-Rad50-Nbs1 proteins prevents the DNA dam...

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Detalles Bibliográficos
Autores principales: Vink, Elizabeth I., Zheng, Yueting, Yeasmin, Rukhsana, Stamminger, Thomas, Krug, Laurie T., Hearing, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452913/
https://www.ncbi.nlm.nih.gov/pubmed/25984715
http://dx.doi.org/10.3390/v7052428