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Impact of Adenovirus E4-ORF3 Oligomerization and Protein Localization on Cellular Gene Expression
The Adenovirus E4-ORF3 protein facilitates virus replication through the relocalization of cellular proteins into nuclear inclusions termed tracks. This sequestration event disrupts antiviral properties associated with target proteins. Relocalization of Mre11-Rad50-Nbs1 proteins prevents the DNA dam...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452913/ https://www.ncbi.nlm.nih.gov/pubmed/25984715 http://dx.doi.org/10.3390/v7052428 |