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In Vivo Tissue Pharmacokinetics of Carbon-11-Labeled Clozapine in Healthy Volunteers: A Positron Emission Tomography Study
We investigated clozapine (CLZ) tissue pharmacokinetics in vivo by using carbon-11-labeled CLZ ((11)C-CLZ) and positron emission tomography (PET). Eight healthy volunteers underwent (11)C-CLZ studies wherein computed tomography image acquisition was followed by PET scans (whole-body, four; brain, fo...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452936/ https://www.ncbi.nlm.nih.gov/pubmed/26225256 http://dx.doi.org/10.1002/psp4.38 |