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Protein-protein interaction between caveolin-1 and SHP-2 is dependent on the N-SH2 domain of SHP-2

Src homology 2-containing protein tyrosine phosphatase 2 (SHP-2) is known to protect neurons from neurodegeneration during ischemia/reperfusion injury. We recently reported that ROS-mediated oxidative stress promotes phosphorylation of endogenous SHP-2 in astrocytes and complex formation between cav...

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Detalles Bibliográficos
Autores principales: Park, Hyunju, Ahn, Keun Jae, Lee Kang, Jihee, Choi, Youn-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453023/
https://www.ncbi.nlm.nih.gov/pubmed/25672415
http://dx.doi.org/10.5483/BMBRep.2015.48.3.249