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New paradigms on siRNA local application

Small interfering RNA (siRNA) functions through pairing with specific mRNA sequences and results in the mRNA’s degradation. It is a potential therapeutic approach for many diseases caused by altered gene expression. The delivery of siRNA is still a major problem due to its rapid degradation in the c...

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Detalles Bibliográficos
Autores principales: Pan, Meng, Ni, Jinwen, He, Huiming, Gao, Shan, Duan, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453025/
https://www.ncbi.nlm.nih.gov/pubmed/25081998
http://dx.doi.org/10.5483/BMBRep.2015.48.3.089