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Activating enhancer binding protein 2 epsilon (AP-2ε)-deficient mice exhibit increased matrix metalloproteinase 13 expression and progressive osteoarthritis development

INTRODUCTION: The transcription factor activating enhancer binding protein 2 epsilon (AP-2ε) was recently shown to be expressed during chondrogenesis as well as in articular chondrocytes of humans and mice. Furthermore, expression of AP-2ε was found to be upregulated in affected cartilage of patient...

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Detalles Bibliográficos
Autores principales: Niebler, Stephan, Schubert, Thomas, Hunziker, Ernst B, Bosserhoff, Anja K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453098/
https://www.ncbi.nlm.nih.gov/pubmed/25964075
http://dx.doi.org/10.1186/s13075-015-0648-8