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MicroR-545 enhanced radiosensitivity via suppressing Ku70 expression in Lewis lung carcinoma xenograft model

OBJECTIVE: Radiotherapy is an important therapeutic method for lung cancer. However, in clinical situations, cellular resistance to radiotherapy is a significant component of tumor treatment failure. Thus, clarification in cellular mechanism underlying radiosensitivity of cancer cell is urgently nee...

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Detalles Bibliográficos
Autores principales: Liao, Chen, Xiao, Wei, Zhu, Nuo, Liu, Zhiyuan, Yang, Jiu, Wang, Yanhu, Hong, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453103/
https://www.ncbi.nlm.nih.gov/pubmed/26041979
http://dx.doi.org/10.1186/s12935-015-0207-z