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Active macropinocytosis induction by stimulation of epidermal growth factor receptor and oncogenic Ras expression potentiates cellular uptake efficacy of exosomes

Exosomes are approximately 100-nm vesicles that consist of a lipid bilayer of cellular membranes secreted in large quantities from various types of normal and disease-related cells. Endocytosis has been reported as a major pathway for the cellular uptake of exosomes; however, the detailed mechanisms...

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Detalles Bibliográficos
Autores principales: Nakase, Ikuhiko, Kobayashi, Nahoko Bailey, Takatani-Nakase, Tomoka, Yoshida, Tetsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453128/
https://www.ncbi.nlm.nih.gov/pubmed/26036864
http://dx.doi.org/10.1038/srep10300