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A sensitised RNAi screen reveals a ch-TOG genetic interaction network required for spindle assembly

How multiple spindle assembly pathways are integrated to drive bipolar spindle assembly is poorly understood. We performed an image-based double RNAi screen to identify genes encoding Microtubule-Associated Proteins (MAPs) that interact with the highly conserved ch-TOG gene to regulate bipolar spind...

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Detalles Bibliográficos
Autores principales: Barr, Alexis R., Bakal, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453164/
https://www.ncbi.nlm.nih.gov/pubmed/26037491
http://dx.doi.org/10.1038/srep10564