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QTc interval prolongation with vascular endothelial growth factor receptor tyrosine kinase inhibitors

BACKGROUND: Multi-targeted vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors (TKIs) are known to cause cardiac toxicity, but the relative risk (RR) of QTc interval prolongation and serious arrhythmias associated with them are not reported. METHODS: We conducted a trial-l...

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Detalles Bibliográficos
Autores principales: Ghatalia, P, Je, Y, Kaymakcalan, M D, Sonpavde, G, Choueiri, T K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453446/
https://www.ncbi.nlm.nih.gov/pubmed/25349964
http://dx.doi.org/10.1038/bjc.2014.564