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Neuropilin-1 as Therapeutic Target for Malignant Melanoma

Neuropilin-1 (NRP-1) is a transmembrane glycoprotein that acts as a co-receptor for various members of the vascular endothelial growth factor (VEGF) family. Its ability to bind or modulate the activity of a number of other extracellular ligands, such as class 3 semaphorins, TGF-β, HGF, FGF, and PDGF...

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Detalles Bibliográficos
Autores principales: Graziani, Grazia, Lacal, Pedro M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453476/
https://www.ncbi.nlm.nih.gov/pubmed/26090340
http://dx.doi.org/10.3389/fonc.2015.00125