Stress Granules Regulate Double-Stranded RNA-Dependent Protein Kinase Activation through a Complex Containing G3BP1 and Caprin1

Stress granules (SGs) are dynamic cytoplasmic repositories containing translationally silenced mRNAs that assemble upon cellular stress. We recently reported that the SG nucleating protein G3BP1 promotes antiviral activity and is essential in double-stranded RNA-dependent protein kinase (PKR) recrui...

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Detalles Bibliográficos
Autores principales: Reineke, Lucas C., Kedersha, Nancy, Langereis, Martijn A., van Kuppeveld, Frank J. M., Lloyd, Richard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453520/
https://www.ncbi.nlm.nih.gov/pubmed/25784705
http://dx.doi.org/10.1128/mBio.02486-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453520/
https://www.ncbi.nlm.nih.gov/pubmed/25784705
http://dx.doi.org/10.1128/mBio.02486-14

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