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Subinhibitory Antibiotic Therapy Alters Recurrent Urinary Tract Infection Pathogenesis through Modulation of Bacterial Virulence and Host Immunity

The capacity of subinhibitory levels of antibiotics to modulate bacterial virulence in vitro has recently been brought to light, raising concerns over the appropriateness of low-dose therapies, including antibiotic prophylaxis for recurrent urinary tract infection management. However, the mechanisms...

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Detalles Bibliográficos
Autores principales: Goneau, Lee W., Hannan, Thomas J., MacPhee, Roderick A., Schwartz, Drew J., Macklaim, Jean M., Gloor, Gregory B., Razvi, Hassan, Reid, Gregor, Hultgren, Scott J., Burton, Jeremy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453531/
https://www.ncbi.nlm.nih.gov/pubmed/25827417
http://dx.doi.org/10.1128/mBio.00356-15