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Subinhibitory Antibiotic Therapy Alters Recurrent Urinary Tract Infection Pathogenesis through Modulation of Bacterial Virulence and Host Immunity
The capacity of subinhibitory levels of antibiotics to modulate bacterial virulence in vitro has recently been brought to light, raising concerns over the appropriateness of low-dose therapies, including antibiotic prophylaxis for recurrent urinary tract infection management. However, the mechanisms...
Autores principales: | Goneau, Lee W., Hannan, Thomas J., MacPhee, Roderick A., Schwartz, Drew J., Macklaim, Jean M., Gloor, Gregory B., Razvi, Hassan, Reid, Gregor, Hultgren, Scott J., Burton, Jeremy P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453531/ https://www.ncbi.nlm.nih.gov/pubmed/25827417 http://dx.doi.org/10.1128/mBio.00356-15 |
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