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Molecular Mechanism of Flocculation Self-Recognition in Yeast and Its Role in Mating and Survival

We studied the flocculation mechanism at the molecular level by determining the atomic structures of N-Flo1p and N-Lg-Flo1p in complex with their ligands. We show that they have similar ligand binding mechanisms but distinct carbohydrate specificities and affinities, which are determined by the comp...

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Detalles Bibliográficos
Autores principales: Goossens, Katty V. Y., Ielasi, Francesco S., Nookaew, Intawat, Stals, Ingeborg, Alonso-Sarduy, Livan, Daenen, Luk, Van Mulders, Sebastiaan E., Stassen, Catherine, van Eijsden, Rudy G. E., Siewers, Verena, Delvaux, Freddy R., Kasas, Sandor, Nielsen, Jens, Devreese, Bart, Willaert, Ronnie G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453552/
https://www.ncbi.nlm.nih.gov/pubmed/25873380
http://dx.doi.org/10.1128/mBio.00427-15