Cargando…

Genetic Basis of Persister Tolerance to Aminoglycosides in Escherichia coli

Persisters are dormant variants that form a subpopulation of drug-tolerant cells largely responsible for the recalcitrance of chronic infections. However, our understanding of the genetic basis of antibiotic tolerance remains incomplete. In this study, we applied transposon sequencing (Tn-Seq) to sy...

Descripción completa

Detalles Bibliográficos
Autores principales: Shan, Yue, Lazinski, David, Rowe, Sarah, Camilli, Andrew, Lewis, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453570/
https://www.ncbi.nlm.nih.gov/pubmed/25852159
http://dx.doi.org/10.1128/mBio.00078-15