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Phylogenomic Identification of Regulatory Sequences in Bacteria: an Analysis of Statistical Power and an Application to Borrelia burgdorferi Sensu Lato

Phylogenomic footprinting is an approach for ab initio identification of genome-wide regulatory elements in bacterial species based on sequence conservation. The statistical power of the phylogenomic approach depends on the degree of sequence conservation, the length of regulatory elements, and the...

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Detalles Bibliográficos
Autores principales: Martin, Che I., Sukarna, Tika Y., Akther, Saymon, Ramrattan, Girish, Pagan, Pedro, Di, Lia, Mongodin, Emmanuel F., Fraser, Claire M., Schutzer, Steven E., Luft, Benjamin J., Casjens, Sherwood R., Qiu, Wei-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453575/
https://www.ncbi.nlm.nih.gov/pubmed/25873371
http://dx.doi.org/10.1128/mBio.00011-15