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CRISPR Immunity Drives Rapid Phage Genome Evolution in Streptococcus thermophilus

Many bacteria rely on CRISPR-Cas systems to provide adaptive immunity against phages, predation by which can shape the ecology and functioning of microbial communities. To characterize the impact of CRISPR immunization on phage genome evolution, we performed long-term bacterium-phage (Streptococcus...

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Detalles Bibliográficos
Autores principales: Paez-Espino, David, Sharon, Itai, Morovic, Wesley, Stahl, Buffy, Thomas, Brian C., Barrangou, Rodolphe, Banfield, Jillian F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453577/
https://www.ncbi.nlm.nih.gov/pubmed/25900652
http://dx.doi.org/10.1128/mBio.00262-15