Intestinal Microbiota Composition Modulates Choline Bioavailability from Diet and Accumulation of the Proatherogenic Metabolite Trimethylamine-N-Oxide

Choline is a water-soluble nutrient essential for human life. Gut microbial metabolism of choline results in the production of trimethylamine (TMA), which upon absorption by the host is converted in the liver to trimethylamine-N-oxide (TMAO). Recent studies revealed that TMAO exacerbates atheroscler...

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Detalles Bibliográficos
Autores principales: Romano, Kymberleigh A., Vivas, Eugenio I., Amador-Noguez, Daniel, Rey, Federico E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453578/
https://www.ncbi.nlm.nih.gov/pubmed/25784704
http://dx.doi.org/10.1128/mBio.02481-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453578/
https://www.ncbi.nlm.nih.gov/pubmed/25784704
http://dx.doi.org/10.1128/mBio.02481-14

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