Cargando…

Histone deacetylase inhibitor SAHA epigenetically regulates miR-17-92 cluster and MCM7 to upregulate MICA expression in hepatoma

BACKGROUND: Epigenetic therapy using histone deacetylase inhibitors (HDACi) has shown promise in clinical trials for the treatment of human malignancies. In addition to the immediate effects on the tumour cell growth, HDACi upregulates the expression of MHC class I-related chain molecules A and B (M...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, H, Lan, P, Hou, Z, Guan, Y, Zhang, J, Xu, W, Tian, Z, Zhang, C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453603/ https://www.ncbi.nlm.nih.gov/pubmed/25393367 http://dx.doi.org/10.1038/bjc.2014.547

Ejemplares similares

Effects of the histone deacetylase inhibitor valproic acid on Notch signalling in human neuroblastoma cells
por: Stockhausen, M-T, et al.
Publicado: (2005)

STAT3 upregulates miR-92a to inhibit RECK expression and to promote invasiveness of lung cancer cells
por: Lin, H-Y, et al.
Publicado: (2013)

Genistein downregulates onco-miR-1260b and upregulates sFRP1 and Smad4 via demethylation and histone modification in prostate cancer cells
por: Hirata, H, et al.
Publicado: (2014)

MiR-17-92 and miR-221/222 cluster members target KIT and ETV1 in human gastrointestinal stromal tumours
por: Gits, C M M, et al.
Publicado: (2013)

Tumour-suppressive microRNA-874 contributes to cell proliferation through targeting of histone deacetylase 1 in head and neck squamous cell carcinoma
por: Nohata, N, et al.
Publicado: (2013)

LSD1-mediated epigenetic modification contributes to proliferation and metastasis of colon cancer
por: Ding, J, et al.
Publicado: (2013)

DJ-1 upregulates breast cancer cell invasion by repressing KLF17 expression
por: Ismail, I A, et al.
Publicado: (2014)

Histone deacetylases 1, 2 and 3 are highly expressed in prostate cancer and HDAC2 expression is associated with shorter PSA relapse time after radical prostatectomy
por: Weichert, W, et al.
Publicado: (2008)

MHC class I chain-related protein A and B (MICA and MICB) are predominantly expressed intracellularly in tumour and normal tissue
por: Ghadially, Hormas, et al.
Publicado: (2017)

Histone Deacetylase (HDAC) Inhibitor, Suberoylanilide Hydroxamic Acid (SAHA), Induces Apoptosis in Prostate Cancer Cell Lines via the Akt/FOXO3a Signaling Pathway
por: Shi, Xuan-Yan, et al.
Publicado: (2017)

miR-1228 promotes the proliferation and metastasis of hepatoma cells through a p53 forward feedback loop
por: Zhang, Y, et al.
Publicado: (2015)

Expression of Mcm2, geminin and Ki67 in normal oral mucosa, oral epithelial dysplasias and their corresponding squamous-cell carcinomas
por: Torres-Rendon, A, et al.
Publicado: (2009)

miR-21, miR-17 and miR-19a induced by phosphatase of regenerating liver-3 promote the proliferation and metastasis of colon cancer
por: Zhang, J, et al.
Publicado: (2012)

Cytochrome-c mediated a bystander response dependent on inducible nitric oxide synthase in irradiated hepatoma cells
por: He, M, et al.
Publicado: (2012)

Histone Deacetylase Inhibitor SAHA as Potential Targeted Therapy Agent for Larynx Cancer Cells
por: Grabarska, Aneta, et al.
Publicado: (2017)

Histone Deacetylase Inhibitor (SAHA) Reduces Mortality in an Endotoxemia Mouse Model by Suppressing Glycolysis
por: Wu, Yunchen, et al.
Publicado: (2023)

Mcm2 predicts recurrence hazard in stage Ta/T1 bladder cancer more accurately than CK20, Ki67 and histological grade
por: Burger, M, et al.
Publicado: (2007)

MCM immunocytochemistry as a first line cervical screening test in developing countries: a prospective cohort study in a regional cancer centre in India
por: Mukherjee, G, et al.
Publicado: (2007)

Upregulated EMMPRIN/CD147 might contribute to growth and angiogenesis of gastric carcinoma: a good marker for local invasion and prognosis
por: Zheng, H-C, et al.
Publicado: (2006)

Post-translational regulation contributes to the loss of LKB1 expression through SIRT1 deacetylase in osteosarcomas
por: Presneau, Nadège, et al.
Publicado: (2017)

Histone deacetylases inhibition by SAHA/Vorinostat normalizes the glioma microenvironment via xCT equilibration
por: Wolf, Ines M. L., et al.
Publicado: (2014)

Prognostic significance of CD44 variant 2 upregulation in colorectal cancer
por: Ozawa, M, et al.
Publicado: (2014)

Histone deacetylase inhibitor SAHA mediates mast cell death and epigenetic silencing of constitutively active D816V KIT in systemic mastocytosis
por: Lyberg, Katarina, et al.
Publicado: (2016)

Dissection of Anti-tumor Activity of Histone Deacetylase Inhibitor SAHA in Nasopharyngeal Carcinoma Cells via Quantitative Phosphoproteomics
por: Huang, Huichao, et al.
Publicado: (2020)

In silico modification of suberoylanilide hydroxamic acid (SAHA) as potential inhibitor for class II histone deacetylase (HDAC)
por: Tambunan, Usman SF, et al.
Publicado: (2011)

The histone deacetylase inhibitor SAHA acts in synergism with fenretinide and doxorubicin to control growth of rhabdoid tumor cells
por: Kerl, Kornelius, et al.
Publicado: (2013)

The epigenetic landscape of oral squamous cell carcinoma
por: Jithesh, P V, et al.
Publicado: (2013)

Upregulation of MAPK pathway is associated with survival in castrate-resistant prostate cancer
por: Mukherjee, R, et al.
Publicado: (2011)

Apricoxib upregulates 15-PGDH and PGT in tobacco-related epithelial malignancies
por: St John, M A, et al.
Publicado: (2012)

Cytoglobin is upregulated by tumour hypoxia and silenced by promoter hypermethylation in head and neck cancer
por: Shaw, R J, et al.
Publicado: (2009)

Intratumoral regulatory T cells upregulate immunosuppressive molecules in head and neck cancer patients
por: Jie, H-B, et al.
Publicado: (2013)

An antiapoptotic Bcl-2 family protein index predicts the response of leukaemic cells to the pan-Bcl-2 inhibitor S1
por: Zhang, Z, et al.
Publicado: (2013)

Akt/Ezrin Tyr353/NF-κB pathway regulates EGF-induced EMT and metastasis in tongue squamous cell carcinoma
por: Wang, Y, et al.
Publicado: (2014)

Erratum for Saha, “Histone Modifications and Other Facets of Epigenetic Regulation in Trypanosomatids: Leaving Their Mark”
por: Saha, Swati
Publicado: (2021)

Upregulation of cancer-associated myofibroblasts by TGF-β from scirrhous gastric carcinoma cells
por: Fuyuhiro, Y, et al.
Publicado: (2011)

Ectopic expression of the chemokine CXCL17 in colon cancer cells
por: Ohlsson, Lina, et al.
Publicado: (2016)

Clinical significance of polypeptide N-acetylgalactosaminyl transferase-5 (GalNAc-T5) expression in patients with gastric cancer
por: He, H, et al.
Publicado: (2014)

Upregulated FGFR1 expression is associated with the transition of hormone-naive to castrate-resistant prostate cancer
por: Armstrong, K, et al.
Publicado: (2011)

Upregulated ankyrin repeat-rich membrane spanning protein contributes to tumour progression in cutaneous melanoma
por: Liao, Y H, et al.
Publicado: (2011)

Molecular consequences of SOD2 expression in epigenetically silenced pancreatic carcinoma cell lines
por: Hurt, E M, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_8j5o7g718flp1e446ur24j0brp