Epigenetics in acute promyelocytic leukaemia pathogenesis and treatment response: A TRAnsition to targeted therapies

Transcriptional deregulation plays a key role in a large array of cancers, and successful targeting of oncogenic transcription factors that sustain diseases has been a holy grail in the field. Acute promyelocytic leukaemia (APL) driven by chimeric transcription factors encoding retinoic acid recepto...

Descripción completa

Detalles Bibliográficos
Autores principales: Arteaga, M F, Mikesch, J-H, Fung, T-K, So, C W E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453638/
https://www.ncbi.nlm.nih.gov/pubmed/25247321
http://dx.doi.org/10.1038/bjc.2014.374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453638/
https://www.ncbi.nlm.nih.gov/pubmed/25247321
http://dx.doi.org/10.1038/bjc.2014.374

Ejemplares similares