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Association between KRAS mutation and lung metastasis in advanced colorectal cancer

BACKGROUND: KRAS mutations have been associated with lung metastases at diagnosis of metastatic colorectal cancer (mCRC), but the impact of this mutation on subsequent development of lung metastasis is unknown. We investigated KRAS mutation as a predictor of lung metastasis development. METHODS: We...

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Detalles Bibliográficos
Autores principales: Pereira, A A L, Rego, J F M, Morris, V, Overman, M J, Eng, C, Garrett, C R, Boutin, A T, Ferrarotto, R, Lee, M, Jiang, Z-Q, Hoff, P M, Vauthey, J-N, Vilar, E, Maru, D, Kopetz, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453646/
https://www.ncbi.nlm.nih.gov/pubmed/25535726
http://dx.doi.org/10.1038/bjc.2014.619