O(6)-Methylguanine-DNA methyltransferase status in neuroendocrine tumours: prognostic relevance and association with response to alkylating agents

BACKGROUND: O(6)-Methylguanine-DNA methyltransferase (MGMT) loss of expression has been suggested to be predictive of response to temozolomide in neuroendocrine tumours (NETs), but so far, only limited data are available. We evaluated the prognostic and predictive value of MGMT status, assessed by t...

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Detalles Bibliográficos
Autores principales: Walter, T, van Brakel, B, Vercherat, C, Hervieu, V, Forestier, J, Chayvialle, J-A, Molin, Y, Lombard-Bohas, C, Joly, M-O, Scoazec, J-Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453664/
https://www.ncbi.nlm.nih.gov/pubmed/25584486
http://dx.doi.org/10.1038/bjc.2014.660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453664/
https://www.ncbi.nlm.nih.gov/pubmed/25584486
http://dx.doi.org/10.1038/bjc.2014.660

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