IFN-γ from lymphocytes induces PD-L1 expression and promotes progression of ovarian cancer

BACKGROUND: PD-L1 (programmed cell death 1 ligand 1) on tumour cells suppresses host immunity through binding to its receptor PD-1 on lymphocytes, and promotes peritoneal dissemination in mouse models of ovarian cancer. However, how PD-L1 expression is regulated in ovarian cancer microenvironment re...

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Detalles Bibliográficos
Autores principales: Abiko, K, Matsumura, N, Hamanishi, J, Horikawa, N, Murakami, R, Yamaguchi, K, Yoshioka, Y, Baba, T, Konishi, I, Mandai, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453666/
https://www.ncbi.nlm.nih.gov/pubmed/25867264
http://dx.doi.org/10.1038/bjc.2015.101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453666/
https://www.ncbi.nlm.nih.gov/pubmed/25867264
http://dx.doi.org/10.1038/bjc.2015.101

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