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Role of Fbxw7 in the maintenance of normal stem cells and cancer-initiating cells
In addition to the properties of self-renewal and multipotency, stem cells are characterised by their distinct cell cycle status. Somatic stem cells are maintained in a quiescent state but switch reversibly from quiescence to proliferation as needed. On the other hand, embryonic stem cells and induc...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453837/ https://www.ncbi.nlm.nih.gov/pubmed/24853181 http://dx.doi.org/10.1038/bjc.2014.259 |