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Role of Fbxw7 in the maintenance of normal stem cells and cancer-initiating cells

In addition to the properties of self-renewal and multipotency, stem cells are characterised by their distinct cell cycle status. Somatic stem cells are maintained in a quiescent state but switch reversibly from quiescence to proliferation as needed. On the other hand, embryonic stem cells and induc...

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Detalles Bibliográficos
Autores principales: Takeishi, S, Nakayama, K I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453837/
https://www.ncbi.nlm.nih.gov/pubmed/24853181
http://dx.doi.org/10.1038/bjc.2014.259