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Identification of proteomic biomarkers predicting prostate cancer aggressiveness and lethality despite biopsy-sampling error

BACKGROUND: Key challenges of biopsy-based determination of prostate cancer aggressiveness include tumour heterogeneity, biopsy-sampling error, and variations in biopsy interpretation. The resulting uncertainty in risk assessment leads to significant overtreatment, with associated costs and morbidit...

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Detalles Bibliográficos
Autores principales: Shipitsin, M, Small, C, Choudhury, S, Giladi, E, Friedlander, S, Nardone, J, Hussain, S, Hurley, A D, Ernst, C, Huang, Y E, Chang, H, Nifong, T P, Rimm, D L, Dunyak, J, Loda, M, Berman, D M, Blume-Jensen, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453845/
https://www.ncbi.nlm.nih.gov/pubmed/25032733
http://dx.doi.org/10.1038/bjc.2014.396