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Identification of proteomic biomarkers predicting prostate cancer aggressiveness and lethality despite biopsy-sampling error
BACKGROUND: Key challenges of biopsy-based determination of prostate cancer aggressiveness include tumour heterogeneity, biopsy-sampling error, and variations in biopsy interpretation. The resulting uncertainty in risk assessment leads to significant overtreatment, with associated costs and morbidit...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453845/ https://www.ncbi.nlm.nih.gov/pubmed/25032733 http://dx.doi.org/10.1038/bjc.2014.396 |