Unique volatolomic signatures of TP53 and KRAS in lung cells

BACKGROUND: Volatile organic compounds (VOCs) are potential biomarkers for cancer detection in breath, but it is unclear if they reflect specific mutations. To test this, we have compared human bronchial epithelial cell (HBEC) cell lines carrying the KRAS(V12) mutation, knockdown of TP53 or both wit...

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Detalles Bibliográficos
Autores principales: Davies, M P A, Barash, O, Jeries, R, Peled, N, Ilouze, M, Hyde, R, Marcus, M W, Field, J K, Haick, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453850/
https://www.ncbi.nlm.nih.gov/pubmed/25051409
http://dx.doi.org/10.1038/bjc.2014.411