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Overall survival and clinical characteristics of pancreatic cancer in BRCA mutation carriers

BACKGROUND: The BRCA1/2 proteins are involved in regulation of cellular proliferation by DNA damage repair via homologous recombination. Therefore, BRCA1/2 mutation carriers with pancreatic cancer may have distinct biologic outcomes. METHODS: Patients with BRCA1/2-associated pancreatic ductal adenoc...

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Detalles Bibliográficos
Autores principales: Golan, T, Kanji, Z S, Epelbaum, R, Devaud, N, Dagan, E, Holter, S, Aderka, D, Paluch-Shimon, S, Kaufman, B, Gershoni-Baruch, R, Hedley, D, Moore, M J, Friedman, E, Gallinger, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453851/
https://www.ncbi.nlm.nih.gov/pubmed/25072261
http://dx.doi.org/10.1038/bjc.2014.418