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The impact of a BRCA2 mutation on mortality from screen-detected prostate cancer

BACKGROUND: Men with a BRCA2 mutation face an increased risk of prostate cancer. These cancers tend to have an aggressive nature and it has not yet been demonstrated that regular screening of BRCA2 carriers is associated with improved survival. METHODS: We identified 4187 men who underwent a prostat...

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Detalles Bibliográficos
Autores principales: Akbari, M R, Wallis, C J D, Toi, A, Trachtenberg, J, Sun, P, Narod, S A, Nam, R K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453856/
https://www.ncbi.nlm.nih.gov/pubmed/25101567
http://dx.doi.org/10.1038/bjc.2014.428