Crystal structure of caspase recruiting domain (CARD) of apoptosis repressor with CARD (ARC) and its implication in inhibition of apoptosis

Apoptosis repressor with caspase recruiting domain (ARC) is a multifunctional inhibitor of apoptosis that is unusually over-expressed or activated in various cancers and in the state of the pulmonary hypertension. Therefore, ARC might be an optimal target for therapeutic intervention. Human ARC is c...

Descripción completa

Detalles Bibliográficos
Autores principales: Jang, Tae-ho, Kim, Seong Hyun, Jeong, Jae-Hee, Kim, Sunghwan, Kim, Yeun Gil, Park, Hyun Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453921/
https://www.ncbi.nlm.nih.gov/pubmed/26038885
http://dx.doi.org/10.1038/srep09847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453921/
https://www.ncbi.nlm.nih.gov/pubmed/26038885
http://dx.doi.org/10.1038/srep09847

Ejemplares similares