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Checkpoint kinase1 (CHK1) is an important biomarker in breast cancer having a role in chemotherapy response

BACKGROUND: Checkpoint kinase1 (CHK1), which is a key component of DNA-damage-activated checkpoint signalling response, may have a role in breast cancer (BC) pathogenesis and influence response to chemotherapy. This study investigated the clinicopathological significance of phosphorylated CHK1 (pCHK...

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Detalles Bibliográficos
Autores principales: Al-kaabi, M M, Alshareeda, A T, Jerjees, D A, Muftah, A A, Green, A R, Alsubhi, N H, Nolan, C C, Chan, S, Cornford, E, Madhusudan, S, Ellis, I O, Rakha, E A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453942/
https://www.ncbi.nlm.nih.gov/pubmed/25688741
http://dx.doi.org/10.1038/bjc.2014.576