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A urine-based methylation signature for risk stratification within low-risk prostate cancer

BACKGROUND: Prostate cancer overdiagnosis and overtreatment represents a major problem. Many men with low-grade disease on biopsy are undergraded and they harbour high-grade disease at prostatectomy with no reliable way to identify these men. We used a novel urine-based 2-gene methylation test to id...

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Detalles Bibliográficos
Autores principales: Jatkoe, T A, Karnes, R J, Freedland, S J, Wang, Y, Le, A, Baden, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453961/
https://www.ncbi.nlm.nih.gov/pubmed/25695483
http://dx.doi.org/10.1038/bjc.2015.7