Identification and validation of dysregulated MAPK7 (ERK5) as a novel oncogenic target in squamous cell lung and esophageal carcinoma

BACKGROUND: MAPK7/ERK5 (extracellular-signal-regulated kinase 5) functions within a canonical three-tiered MAPK (mitogen activated protein kinase) signaling cascade comprising MEK (MAPK/ERK kinase) 5, MEKK(MEK kinase) 2/3 and ERK5 itself. Despite being the least well studied of the MAPK-modules, evi...

Descripción completa

Detalles Bibliográficos
Autores principales: Gavine, Paul R., Wang, Mei, Yu, Dehua, Hu, Eva, Huang, Chunlei, Xia, Jenny, Su, Xinying, Fan, Joan, Zhang, Tianwei, Ye, Qingqing, Zheng, Li, Zhu, Guanshan, Qian, Ziliang, Luo, Qingquan, Hou, Ying Yong, Ji, Qunsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453990/
https://www.ncbi.nlm.nih.gov/pubmed/26040563
http://dx.doi.org/10.1186/s12885-015-1455-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453990/
https://www.ncbi.nlm.nih.gov/pubmed/26040563
http://dx.doi.org/10.1186/s12885-015-1455-y

Ejemplares similares