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Single-Molecule Imaging Reveals Dynamics of CREB Transcription Factor Bound to Its Target Sequence

Proper spatiotemporal gene expression is achieved by selective DNA binding of transcription factors in the genome. The most intriguing question is how dynamic interactions between transcription factors and their target sites contribute to gene regulation by recruiting the basal transcriptional machi...

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Detalles Bibliográficos
Autores principales: Sugo, Noriyuki, Morimatsu, Masatoshi, Arai, Yoshiyuki, Kousoku, Yoshinori, Ohkuni, Aya, Nomura, Taishin, Yanagida, Toshio, Yamamoto, Nobuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454023/
https://www.ncbi.nlm.nih.gov/pubmed/26039515
http://dx.doi.org/10.1038/srep10662