Severe Myelotoxicity Associated with Thiopurine S-Methyltransferase*3A/*3C Polymorphisms in a Patient with Pediatric Leukemia and the Effect of Steroid Therapy

Myelosuppression is a serious complication during treatment of acute lymphoblastic leukemia and the duration of myelosuppression is affected by underlying bone marrow failure syndromes and drug pharmacogenetics caused by genetic polymorphisms. Mutations in the thiopurine S-methyltransferase (TPMT) g...

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Detalles Bibliográficos
Autores principales: Belen, Burcu Fatma, Gürsel, Türkiz, Akyürek, Nalan, Albayrak, Meryem, Kaya, Zühre, Koçak, Ülker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454056/
https://www.ncbi.nlm.nih.gov/pubmed/25541649
http://dx.doi.org/10.4274/tjh.2013.0082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454056/
https://www.ncbi.nlm.nih.gov/pubmed/25541649
http://dx.doi.org/10.4274/tjh.2013.0082

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