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Highly efficient direct conversion of human fibroblasts to neuronal cells by chemical compounds

Direct conversion of mammalian fibroblasts into induced neuronal (iN) cells has been attained by forced expression of pro-neural transcriptional factors, or by combining defined factors with either microRNAs or small molecules. Here, we show that neuronal cells can be converted from postnatal human...

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Detalles Bibliográficos
Autores principales: Dai, Ping, Harada, Yoshinori, Takamatsu, Tetsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454078/
https://www.ncbi.nlm.nih.gov/pubmed/26060345
http://dx.doi.org/10.3164/jcbn.15-39