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l-Arginine administration attenuates airway inflammation by altering l-arginine metabolism in an NC/Nga mouse model of asthma

Changes in l-arginine metabolism, including increased arginase levels and decreased nitric oxide production, are involved in the pathophysiology of asthma. In this study, using an intranasal mite-induced NC/Nga mouse model of asthma, we examined whether administration of l-arginine ameliorated airwa...

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Detalles Bibliográficos
Autores principales: Zhang, Ran, Kubo, Masayuki, Murakami, Ikuo, Setiawan, Heri, Takemoto, Kei, Inoue, Kiyomi, Fujikura, Yoshihisa, Ogino, Keiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454082/
https://www.ncbi.nlm.nih.gov/pubmed/26060350
http://dx.doi.org/10.3164/jcbn.14-140