Opioid Exacerbation of Gram-positive sepsis, induced by Gut Microbial Modulation, is Rescued by IL-17A Neutralization

Sepsis is the predominant cause of mortality in ICUs, and opioids are the preferred analgesic in this setting. However, the role of opioids in sepsis progression has not been well characterized. The present study demonstrated that morphine alone altered the gut microbiome and selectively induced the...

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Detalles Bibliográficos
Autores principales: Meng, Jingjing, Banerjee, Santanu, Li, Dan, Sindberg, Gregory M., Wang, Fuyuan, Ma, Jing, Roy, Sabita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454150/
https://www.ncbi.nlm.nih.gov/pubmed/26039416
http://dx.doi.org/10.1038/srep10918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454150/
https://www.ncbi.nlm.nih.gov/pubmed/26039416
http://dx.doi.org/10.1038/srep10918

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