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Polarity protein Par3 controls B-cell receptor dynamics and antigen extraction at the immune synapse
B-cell receptor (BCR) engagement with surface-tethered antigens leads to the formation of an immune synapse, which facilitates antigen uptake for presentation to T-lymphocytes. Antigen internalization and processing rely on the early dynein-dependent transport of BCR–antigen microclusters to the syn...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454175/ https://www.ncbi.nlm.nih.gov/pubmed/25631815 http://dx.doi.org/10.1091/mbc.E14-09-1373 |