Polarity protein Par3 controls B-cell receptor dynamics and antigen extraction at the immune synapse

B-cell receptor (BCR) engagement with surface-tethered antigens leads to the formation of an immune synapse, which facilitates antigen uptake for presentation to T-lymphocytes. Antigen internalization and processing rely on the early dynein-dependent transport of BCR–antigen microclusters to the syn...

Descripción completa

Detalles Bibliográficos
Autores principales: Reversat, Anne, Yuseff, Maria-Isabel, Lankar, Danielle, Malbec, Odile, Obino, Dorian, Maurin, Mathieu, Penmatcha, Naga Venkata Gayathri, Amoroso, Alejandro, Sengmanivong, Lucie, Gundersen, Gregg G., Mellman, Ira, Darchen, François, Desnos, Claire, Pierobon, Paolo, Lennon-Duménil, Ana-Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454175/
https://www.ncbi.nlm.nih.gov/pubmed/25631815
http://dx.doi.org/10.1091/mbc.E14-09-1373

Ejemplares similares

Ejemplares similares