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Isolation and evaluation of anticancer efficacy of stigmasterol in a mouse model of DMBA-induced skin carcinoma

Stigmasterol (99.9% pure) was isolated from Azadirachta indica and its chemopreventive effect on 7,12-dimethylbenz[a]anthracene (DMBA)-induced skin cancer was investigated in Swiss albino mice. Skin tumors were induced by topical application of DMBA and promoted by croton oil. To assess the chemopre...

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Detalles Bibliográficos
Autores principales: Ali, Huma, Dixit, Savita, Ali, Daoud, Alqahtani, Saeed M, Alkahtani, Saad, Alarifi, Saud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454197/
https://www.ncbi.nlm.nih.gov/pubmed/26060396
http://dx.doi.org/10.2147/DDDT.S83514