Melanophilin Stimulates Myosin-5a Motor Function by Allosterically Inhibiting the Interaction between the Head and Tail of Myosin-5a

The tail-inhibition model is generally accepted for the regulation of myosin-5a motor function. Inhibited myosin-5a is in a folded conformation in which its globular tail domain (GTD) interacts with its head and inhibits its motor function, and high Ca(2+) or cargo binding may reduce the interaction...

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Detalles Bibliográficos
Autores principales: Yao, Lin-Lin, Cao, Qing-Juan, Zhang, Hai-Man, Zhang, Jie, Cao, Yang, Li, Xiang-dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454200/
https://www.ncbi.nlm.nih.gov/pubmed/26039755
http://dx.doi.org/10.1038/srep10874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454200/
https://www.ncbi.nlm.nih.gov/pubmed/26039755
http://dx.doi.org/10.1038/srep10874

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