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Gastrointestinal Stromal Tumors (GIST): A Prospective Analysis and an Update on Biomarkers and Current Treatment Concepts

Gastrointestinal stromal tumors (GIST) are the most common sarcomas of the gastrointestinal tract, with transformation typically driven by activating mutations of cKIT and less commonly platelet-derived growth factor receptor alpha (PDGFRA). Successful targeting of tyrosine-protein kinase Kit with i...

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Detalles Bibliográficos
Autores principales: Koumarianou, Anna, Economopoulou, Panagiota, Katsaounis, Panagiotis, Laschos, Konstantinos, Arapantoni-Dadioti, Petroula, Martikos, George, Rogdakis, Athanasios, Tzanakis, Nikolaos, Boukovinas, Ioannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454203/
https://www.ncbi.nlm.nih.gov/pubmed/26056505
http://dx.doi.org/10.4137/BIC.S25045