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Brimonidine reduces TGF-beta-induced extracellular matrix synthesis in human Tenon’s fibroblasts
BACKGROUND: Brimonidine is a highly selective α(2) adrenergic agonist that has been widely used in anti-glaucoma eyedrops. The aim of this study was to investigate its putative anti-fibrotic role in the fibrosis caused by activated Tenon’s fibroblasts. METHODS: Primary cultured human Tenon’s fibrobl...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454273/ https://www.ncbi.nlm.nih.gov/pubmed/26017119 http://dx.doi.org/10.1186/s12886-015-0045-8 |