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Autophagy promotes paclitaxel resistance of cervical cancer cells: involvement of Warburg effect activated hypoxia-induced factor 1-α-mediated signaling

Paclitaxel is one of the most effective chemotherapy drugs for advanced cervical cancer. However, acquired resistance of paclitaxel represents a major barrier to successful anticancer treatment. In this study, paclitaxel-resistant HeLa sublines (HeLa-R cell lines) were established by continuous expo...

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Detalles Bibliográficos
Autores principales: Peng, X, Gong, F, Chen, Y, Jiang, Y, Liu, J, Yu, M, Zhang, S, Wang, M, Xiao, G, Liao, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454295/
https://www.ncbi.nlm.nih.gov/pubmed/25118927
http://dx.doi.org/10.1038/cddis.2014.297