A novel androstenedione derivative induces ROS-mediated autophagy and attenuates drug resistance in osteosarcoma by inhibiting macrophage migration inhibitory factor (MIF)

Osteosarcoma is a common primary bone tumor in children and adolescents. The drug resistance of osteosarcoma leads to high lethality. Macrophage migration inhibitory factor (MIF) is an inflammation-related cytokine implicated in the chemoresistance of breast cancer. In this study, we isolated a nove...

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Detalles Bibliográficos
Autores principales: Liu, Y, Zhao, L, Ju, Y, Li, W, Zhang, M, Jiao, Y, Zhang, J, Wang, S, Wang, Y, Zhao, M, Zhang, B, Zhao, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454296/
https://www.ncbi.nlm.nih.gov/pubmed/25101674
http://dx.doi.org/10.1038/cddis.2014.300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454296/
https://www.ncbi.nlm.nih.gov/pubmed/25101674
http://dx.doi.org/10.1038/cddis.2014.300

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