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Transcription addiction: can we garner the Yin and Yang functions of E2F1 for cancer therapy?
Classically, as a transcription factor family, the E2Fs are known to regulate the expression of various genes whose products are involved in a multitude of biological functions, many of which are deregulated in diseases including cancers. E2F is deregulated and hyperactive in most human cancers with...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454301/ https://www.ncbi.nlm.nih.gov/pubmed/25101673 http://dx.doi.org/10.1038/cddis.2014.326 |