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PARP1 activation/expression modulates regional-specific neuronal and glial responses to seizure in a hemodynamic-independent manner

Poly(ADP-ribose) polymerase-1 (PARP1) plays a regulatory role in apoptosis, necrosis and other cellular processes after injury. Status epilepticus (SE) induces neuronal and astroglial death that show regional-specific patterns in the rat hippocampus and piriform cortex (PC). Thus, we investigated wh...

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Detalles Bibliográficos
Autores principales: Kim, J-E, Kim, Y-J, Kim, J Y, Kang, T-C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454306/
https://www.ncbi.nlm.nih.gov/pubmed/25101675
http://dx.doi.org/10.1038/cddis.2014.331