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PARP1 activation/expression modulates regional-specific neuronal and glial responses to seizure in a hemodynamic-independent manner
Poly(ADP-ribose) polymerase-1 (PARP1) plays a regulatory role in apoptosis, necrosis and other cellular processes after injury. Status epilepticus (SE) induces neuronal and astroglial death that show regional-specific patterns in the rat hippocampus and piriform cortex (PC). Thus, we investigated wh...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454306/ https://www.ncbi.nlm.nih.gov/pubmed/25101675 http://dx.doi.org/10.1038/cddis.2014.331 |