Inhibitory effect of 2-(piperidinoethoxyphenyl)-3-(4-hydroxyphenyl)-2H-benzo(b)pyran (K-1) on human primary endometrial hyperplasial cells mediated via combined suppression of Wnt/β-catenin signaling and PI3K/Akt survival pathway

Endometrial hyperplasia is a precursor to the most common gynecologic cancer diagnosed in women. Apart from estrogenic induction, aberrant activation of the Wnt/β-catenin signal is well known to correlate with endometrial hyperplasia and its carcinoma. The benzopyran compound 2-(piperidinoethoxyphen...

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Detalles Bibliográficos
Autores principales: Chandra, V, Fatima, I, Manohar, M, Popli, P, Sirohi, V K, Hussain, M K, Hajela, K, Sankhwar, P, Dwivedi, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454309/
https://www.ncbi.nlm.nih.gov/pubmed/25144715
http://dx.doi.org/10.1038/cddis.2014.334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454309/
https://www.ncbi.nlm.nih.gov/pubmed/25144715
http://dx.doi.org/10.1038/cddis.2014.334

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